Which test is specifically designed to screen for Mononucleosis?

The Mono Screen test is specifically designed to detect the presence of heterophile antibodies, which are produced during an infection with Epstein-Barr virus (EBV), the most common cause of infectious mononucleosis. This test is quick and straightforward, making it a valuable tool in identifying individuals who may have mononucleosis based on their clinical symptoms, which often include excessive fatigue, sore throat, fever, and swollen lymph nodes.

In contrast, the other tests listed serve different purposes: RF (Rheumatoid Factor) is associated with diagnosing rheumatoid arthritis and other autoimmune conditions, the Direct Coombs test is used to determine hemolytic anemia caused by the immune system attacking red blood cells, and C-Reactive Protein (CRP) is a nonspecific marker of inflammation and does not directly indicate an infectious mononucleosis infection. Therefore, the Mono Screen is uniquely tailored to screen for this specific viral infection.