What is the purpose of testing for CD4/CD8 T Cells?

Testing for CD4/CD8 T Cells is primarily aimed at tracking HIV progression in individuals infected with the virus. CD4 T cells are a type of white blood cell that plays a crucial role in the immune system by helping the body fight infections. In the context of HIV, the virus specifically targets these cells, leading to a decline in their numbers as the infection progresses. Monitoring the levels of CD4 cells provides insight into the immune status of the individual and helps healthcare providers determine the stage of HIV disease and the effectiveness of antiretroviral therapy.

In this context, the ratio of CD4 to CD8 T cells also provides important information about immune function, as CD8 T cells are typically involved in the direct killing of infected cells. An imbalance in this ratio can indicate immune system dysfunction associated with HIV. This information is vital for treatment decisions and predicting outcomes for patients living with HIV, making it clear why this testing is essential for managing the disease effectively.